Guide how to unlock ALL 641 achievements

The Binding of Isaac: Rebirth★ 5 · 644 ratings23k views1.6k favorites14 min readby MamonUpdated 20 JulView on Steam ↗

Translation

The author of this guide does not speak English. However, I did my best to translate everything using a translator and Wiki. I would be very grateful for any help with writing or for support in the form of Steam points. Thank you!

↓ Original ↓
https://steamcommunity.com/sharedfiles/filedetails/?id=3408959992

Introduction

In this guide, you can find ways to achieve something new in the game and unlock it.














If you find a way to have suggestions for improvement, the comments are open.

Characters

Isaac
unlocked by default

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Magdalene
Have 7 or more Red Heart
containers at one time.

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Cain
Hold 55 Coins at one time

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Judas
Defeat Satan

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

???
Defeat Mom's Heart 10 times

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Eve
Don't pick up any Hearts for 2 floors in a row

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Characters

Samson
Complete 2 floors in a row without taking damage

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Lazarus
Have 4 or more Soul Hearts at one time

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Azazel
Make 3 Deals with the Devil in one run

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Eden
Complete Chapter 4

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

The Lost
Die in a Sacrifice Room while holding Missing Poster

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Lilith
Defeat Ultra Greed as Azazel

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Characters

Keeper
Donate 1000 Coins to the Greed Donation Machine

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Apollyon
Defeat Mega Satan

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

The Forgotten
Dig a grave with mom's shovel at the level of the dark room
"More details"[bindingofisaacrebirth.fandom.com]

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Bethany
Defeat Mom's Heart/It Lives! on
hard mode as Lazarus, without dying at all

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Jacob and Esau
Defeat Mother

Unlock
Target
Boss Rush
Mom's Heart
Satan
Isaac
???
The Lamb
Ultra Greed
Ultra Greedier
Hush
Mega Satan
Delirium
Mother
The Beast
Completion Marks

Tainted Characters

Tainted Isaac
Use Red Key (etc.) to open the hidden closet in Home as Isaac

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Magdalene
Use Red Key (etc.) to open the hidden closet in Home as Magdalene

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Cain
Use Red Key (etc.) to open the hidden closet in Home as Cain

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Judas
Use Red Key (etc.) to open the hidden closet in Home as Judas

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted ???
Use Red Key (etc.) to open the hidden closet in Home as ???

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Eve
Use Red Key (etc.) to open the hidden closet in Home as Eve

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Samson
Use Red Key (etc.) to open the hidden closet in Home as Samson

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Lazarus
Use Red Key (etc.) to open the hidden closet in Home as Lazarus

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Azazel
Use Red Key (etc.) to open the hidden closet in Home as Azazel

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Characters

Tainted Eden
Use Red Key (etc.) to open the hidden closet in Home as Eden

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Lost
Use Red Key (etc.) to open the hidden closet in Home as The Lost

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Lilith
Use Red Key (etc.) to open the hidden closet in Home as Lilith

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Keeper
Use Red Key (etc.) to open the hidden closet in Home as Keeper

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Apollyon
Use Red Key (etc.) to open the hidden closet in Home as Apollyon

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Forgotten
Use Red Key (etc.) to open the hidden closet in Home as The Forgotten

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Bethany
Use Red Key (etc.) to open the hidden closet in Home as Bethany

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Tainted Jacob
Use Red Key (etc.) to open the hidden closet in Home as Jacob and Esau

Isaac, ???, Satan, The Lamb
Ultra Greedier
Hush and Boss Rush
Mega Satan
Delirium
Mother
The Beast

Normal characters have 14 unlocks
Tainted characters have 7
392

Challenges

Unlock
№
Name
1
Pitch Black
2
High Brow
3
Head Trauma
4
Darkness Falls
___
Defeat Mom's Heart 11 times and defeat ??? as Eve
5
The Tank
_______________
Have 7 or more Red Heart Containers at one time
6
Solar System
_______________
Defeat Mom's Heart 3 times
7
Suicide King
___
Defeat Mom's Heart 11 times and unlock Lazarus
8
Cat Got Your Tongueл
_______________
Become Guppy
9
Demo Man
___
Defeat Mom's Heart 9 times
10
Cursed!
_______________
Have 7 or more Red Heart Containers at one time
11
Glass Cannon
___
Beat The Family Man (challenge #19), defeat Lokii, and unlock Judas
12
When Life Gives You Lemons
13
Beans!
14
It's in the Cards
15
Slow Roll
16
Computer Savvy
17
Waka Waka
18
The Host
19
The Family Man
___
Pick up both Key Pieces from the Angels in one run
20
Purist
_______________
Defeat Mom
21
XXXXXXXXL
_______________
Defeat Mom
22
SPEED!
_______________
Defeat Mom
23
Blue Bomber
___
Destroy 10 Tinted Rocks and defeat Mom's Heart 11 times
24
PAY TO PLAY
___
Defeat Isaac as Cain and destroy 10 Tinted Rocks
25
Have a Heart
_______________
Defeat Mom
26
I RULE!
___
Defeat Mega Satan and unlock The Negative
27
BRAINS!
_______________
Defeat Isaac 5 times
28
PRIDE DAY!
_______________
Defeat Mom
29
Onan's Streak
___
Unlock Judas and It Lives.
30
The Guardian
_______________
Defeat Mom
31
Backasswards
___
Defeat Mega Satan and unlock The Negative
32
Aprils Fool
_______________
Defeat Mom
33
Pokey Mans
___
Defeat Mom's Heart 11 times
34
Ultra Hard
___
Defeat Mega Satan and unlock The Negative
35
Pong
_______________
Defeat Isaac 5 times
36
Scat Man
37
Bloody Mary
___
Unlock Bethany, Blood Bag, and It Lives!
38
Baptism by Fire
___
Defeat Satan as Bethany, defeat Mom's Heart
11 times, and unlock Maggy's Faith
39
Isaac's Awakening
_______________
Defeat Mother
40
Seeing Double
_______________
Defeat Mother

Challenges

41
Pica Run
___
Defeat Mom's Heart 11 times and unlock Marbles
42
Hot Potato
_____________
Unlock Tainted Forgotten
43
Cantripped!
_____________
Unlock Tainted Cain
44
Red Redemption
_____________
Unlock Tainted Jacob
45
DELETE THIS
_____________
Unlock Tainted Eden

45 for completion
34 for open
79

Donations

Donation Machine

Unlock
Coins
10
20
lvl
50
100
lvl
150
200
lvl
400
600
lvl
900
999

Greed Donation Machine

Unlock
Coins
2
14
33
68
111
234
439
500
666
879
999
1000

Donation Machine - 10
Greed Donation Machine - 11
21

Final Bosses

Mom



First murder
Kill using the Bible

Mom's Heart


Defeat Mom's Heart 1 times.
Defeat Mom's Heart 2 times.
Defeat Mom's Heart 3 times.
Defeat Mom's Heart 4 times.
Defeat Mom's Heart 5 times.
Defeat Mom's Heart 6 times.
Defeat Mom's Heart 7 times.
Defeat Mom's Heart 8 times.
Defeat Mom's Heart 9 times.
Defeat Mom's Heart 10 times.


Defeat Mom's Heart 11 times.
Kill using the Bible

It Lives

Open Judas and It Lives
Defeat It Lives! 16 times
Defeat It Lives! 21 times
Defeat It Lives! 30 times
Kill using the Bibl

Satan

Defeat Satan
Defeat Satan 5 times
Defeat Mega Satan and unlock The Negative

Isaac



Defeat Isaac 5 times
Defeat Isaac 10 times
Defeat Isaac as Cain and destroy 10 Tinted Rocks

???

Defeat ??? and The Lamb
Defeat ??? as 3 different Characters
Defeat ??? as 6 different Characters
Complete Chapter 6

The Lamb

Defeat ??? and The Lamb
Defeat The Lamb
Defeat The Lamb in under 20 minutes
Defeat The Lamb without taking Hearts, Coins, or Bombs through the entire run
Complete a Victory Lap by defeating The Lamb
Complete Chapter 6

Mega Satan

Defeat Mega Satan
Kill Mega Satan with all normal characters


Defeat Mega Satan and unlock The Negative

Hush

Defeat Hush
Defeat Hush 3 times.



Mother


Defeat Mother


Delirium

Defeat Delirium

Chapters

Chapter 1
Basement, Cellar,
    Beat Chapter 1
    Beat Basement 40 times
    Beat all Basement bosses

    Beat Chapter 1 without taking damage
    Defeat Mom's Heart 11 times
    Alternative
    Downpour, Dross

    Defeat Hush 3 times
    Defeat all bosses in Downpour
    Chapter 2
    Caves, Catacombs, Flooded Caves

    Beat Chapter 2
    Beat Chapter 2 30 times
    Beat all Caves bosses

    Beat Chapter 2 without taking damage
    Defeat It Lives! 16 times
    Alternative
    Mines, Ashpit

    Defeat all bosses in Mines
    Chapter 3
    Depths, Necropolis, Dank Depths

    Beat Chapter 3 20 times
    Beat all Depths bossesн

    Beat Chapter 3 without taking damage
    Defeat It Lives! 21 times
    Alternative
    Mausoleum, Gehenna
    Defeat all bosses in Mausoleum
    Chapter 4
    Womb, Utero, Scarred Womb

    Defeat Mom

    Beat Chapter 4 without taking damage
    Defeat It Lives! 30 times
    Alternative
    Corpse

    Enter Corpse for the first time
    Chapter 6
    Chest, Dark Room

    Defeat Isaac 5 times
    Defeat Satan 5 times

    Dig up the Earth Mound in the Dark Room
    more details[bindingofisaacrebirth.fandom.com]

Bosses

Defeat a Harbinger
Defeat Lokii
Defeat all 7 Deadly Sins
Defeat Gish
Defeat Steven
Defeat C.H.A.D.
Defeat Krampus
Defeat Little Horn 20 times
Defeat all 5 Harbingers
Defeat an Angel 10 times
Defeat Baby Plum 10 times
Allow Baby Plum to escape
instead of defeating her
After breaking Hornfel's minecart,
kill him before he can escape

Other

Collect 4 Band-Aid Balls in one run
Collect 4 Meat Cubes in one run
Collect 2 documents for one run:
Turn into Yes Mother?

Turn into Guppy

Turn into Beelzebub

Collect the First and Second Parts of the Key
Collect 2 documents for one run:
Use Blank Card while holding XIX - The Sun
Get a 3-win streak
Get a 3-win streak, using a different character each time
Collect every entry in the Bestiary
Restart the game 7 times by pressing the restart button
[R]
Defeat The Lamb in under 20 minutes
Defeat The Lamb without taking Hearts, Coins
or Bombs through the entire run
Complete a Chapter (floors I and II) after Basement,
start-to-finish, with only half a Heart tota
Obtain 50 items in a run
Add both the Broken Watch and the Stop Watch to your collection

Use Pandora's Box in Dark Room
Collect 2 artifacts/trinkets in one run:
Collect 2 technologies in one run:
Enter 6 Shops in one run
Add to collection:
Have Isaac die to his own explosion from Ipecac,
Bob's Rotten Head, or a Horf! pill

Use 5 Gulp! pills in one run
Spawn three charmed enemies in the same room
Have 20 Blue Flies at the same time
Get two homing effects at once
Collect three artifacts related to the stars:
Blow up The Siren's skull after defeating her
Open Mom's Chest in Home
In a single run, obtain 99 Coins, then spend all of them
Spend 40+ coins in a single Shop

Statistics

Destroy 10 Tinted Rocks
Destroy 100 Tinted Rocks
Destroy 100 rocks
Destroy 500 rocks
Destroy 100 Poops
Destroy 5 rainbow poops
Visit 10 Arcades
Die 100 times
Use XIII - Death 4 times
Blow up 20 Shopkeepers
Play either Shell Game or Hell Game 100 times
Take 10 Angel Room items
Take 25 Angel Room items
Take 20 items from Devil Rooms
Take 25 Deals with the Devil
Take 50 Deals with the Devil
Use the Blood Donation Machine 30 times
Blow up 30 Slot Machine
Defeat 20 Portals
Pick up 5 familiars in a single run
Recharge using Lil' Batteries 20 times
Sleep in a bed
Sleep in 10 beds
Increase in size 5 times in a single run
Use Cards and Runes 20 times
Purchase anything from Shops, Devil Rooms,
and/or Black Markets 50 times
Open 20 Locked Chests
Blow up doors and Secret Room walls 50 times
Acquire Blood Clot 10 times
Collect 10 "Tears Up" items or pills in one run
Acquire Rubber Cement 5 times
Donate to Battery Bums until they pay out
with an item 5 times
Kill 10 Battery Bums

Victory Lap


Complete a Victory Lap by defeating The Lamb
Complete 2 Victory Laps by defeating The Lamb
Complete 3 Victory Laps by defeating The Lamb

Daily Challenges


Get a 5-win streak in the Daily Challenges
(they don't have to be consecutive days,
only the runs you play are counted)
Complete 7 Daily Challenges
(by touching the trophy at the end)
Participate in 31 Daily Challenges
(they don't have to be consecutive; it will still
count if Isaac dies in the first room)

File progress

Golden God!
Defeat ??? and The Lamb
!Platinum God!
Collect all non-DLC items in the game,
and unlock all of the secrets and endings
(minus The Lost and his 6 unlockable items)
The Real Platinum God
Collect every non-DLC item, and unlock every
secret and ending
1001%
Unlock any 276 achievements
1000000%
Unlock any 403 achievements
Dead God
Unlock all the other achievements and collect
every item in the game

Co-op (Repentance +)

Playing an Online Match
Winning an Online Match
Winning an online Daily Run
Defeat Mom

Author of the message: LudoAlvera

SIDE NOTE: Rep+ achievments are bugged - even if you do win an online match, it will not pop up for you at first. What you have to do is go to the main screen of the game > stats > secrets > press left (it will show you the "won an online match" secret)

Doing that will automatically grant you the Win and Play an Online Match achievment on Steam!


Useful pictures


https://steamcommunity.com/sharedfiles/filedetails/?id=3338799548




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